There is a 5-angstrom-diameter "hole" through the middle of the barrel. The barrel structure of GIF in part resembles other "trefoil" cytokines such as interleukin 1 and fibroblast growth factor.
These beta-alpha-beta motifs are related by a pseudo-twofold axis and resemble both interleukin 8 and the peptide binding domain of major histocompatibility complex protein, although the topology of the polypeptide chain is quite different.
Warning You are using a web browser that we do not support. Our website will not work properly. Please update to a newer version or download a new web browser, such as Chrome or Firefox. Asymmetric Unit. What's new. Sequence features and user annotations in Repository are now easier to navigate. This project has furthermore received funding from ELIXIR and the European Union's Horizon research and innovation programme under grant agreement number Nucleic Acids Res. Bienert, S.
Guex, N. Electrophoresis 30, SS Gray — nuclear pore. Yellow — unstructured FG repeat domains. Blue — contaminants. It shows two broadly neutralizing antibodies bound to HIV spikes and two small molecule inhibitors bound to the virus capsid protein.
The movie was made using a Chimera sesssion hiv14h. The movie was made for Robert Fletterick using a Chimera sesssion dax1. Beta catenin. March 11, Beta catenin is a protein associated with many cancers and binds to nuclear receptors which are transcription factors.
This movie shows that a nuclear receptor dimer clashes with beta catenin if docked in the same location where a monomer nuclear receptor binds. The movie was made for Robert Fletterick using a Chimera sesssion beta-catenin3. HIV reverse transcriptase drugs. March 6, Shows small molecules bound to HIV reverse transcriptase including many drugs.
This animation was made with command " turn z 2 precess 20 ". Leucyl-tRNA synthetase. June 28, Andres Palencia shows how leucine is attached to a transfer RNA.
The movie was made with Chimera command script leucyl-tRNA. Structural dynamics of the aminoacylation and proofreading functional cycle of bacterial leucyl-tRNA synthetase. Nat Struct Mol Biol. February 22, Animation of molecular machinery that copies the HIV virus RNA genome with music and narration, created for display on a planetarium dome at the Biophysical Society meeting. More details. More resolutions on YouTube. Dome animation. November 3, Three short animation segments for display on a dome projection system: dengue virus capsid maturation, bacteriophage phi6 electron microscopy, and RNA polymerase fly-through.
May 20, Rotavirus polymerase fly-through. March 10, The blue and red polymerase coloring is Coulomb electrostatic potential. The fly-through follows a slightly weaving path to avoid crashing through the RNA bases.
The fly command produces a cubic spline trajectory through 4 hand-chosen positions. A video shows all the steps to make this animation. A Chimera session file rotafly. Nup84 nuclear pore subassembly. March 9, Morph between density maps for straight stem and kinked stem conformations of a 7 protein nuclear pore subassembly EMDB , created with the Morph Map tool.
A video shows the steps used to produce this animation. Ball-and-socket motion. August 26, The Chimera command file trmovie. Chimera command files are plain text, and simply opening the file in Chimera will execute its contents. To run this script without recording which makes execution slow , first insert before each of the five "movie" commands.
Herpes virus slices. January 27, Slicing a virus density map EMDB while showing 3 orthogonal planes created with Chimera command script orthoslice. Alternatively a Python script orthoslice.
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